Treatment-Resistant Depression Therapy

Specialized Care for Treatment-Resistant Depression with Spravato®

At Daniel Perry MD, we offer advanced treatment options for individuals facing treatment-resistant depression in Savannah, GA.

Under the guidance of Dr. Daniel Perry, MD, MPH, patients receive trusted, evidence-based care that combines modern medical innovation with compassionate psychiatric expertise.

If traditional antidepressant medications haven’t provided relief, Spravato® (esketamine) therapy may offer a new path forward. Dr. Perry provides this FDA-approved treatment in a secure, private clinical environment to help patients find renewed stability and hope.

Understanding Treatment-Resistant Depression

Depression affects millions of people, and while many respond well to standard medications, others continue to experience persistent symptoms even after multiple treatment trials.

This condition is known as treatment-resistant depression (TRD).

TRD can leave patients feeling discouraged, but new advancements in psychiatric medicine now provide safe and effective options for individuals who haven’t found success with traditional antidepressants.

At Daniel Perry MD, we understand how complex depression can be. Dr. Perry carefully evaluates each patient’s history, prior medication use, and individual needs before recommending the most appropriate next steps, including Spravato® therapy when indicated.

What Is Spravato® (Esketamine)?

Spravato® is an FDA-approved nasal spray designed for adults with treatment-resistant depression.

It works differently from conventional antidepressants by targeting the brain’s NMDA receptors, which are linked to mood regulation and neural plasticity.

Spravato® is administered in our Savannah, GA office under direct medical supervision. Patients remain in a calm, monitored environment during and after each session to ensure comfort and safety.

Many patients experience improved mood, reduced depressive symptoms, and renewed motivation after completing a course of Spravato® therapy.

How Dr. Perry Helps

Dr. Perry’s approach to treatment-resistant depression is built on clinical precision and compassionate communication.

Each treatment plan is customized, evidence-based, and structured for ongoing support.

Your care may include:

• Comprehensive psychiatric evaluation to confirm TRD diagnosis
• Review of prior medication responses and current symptoms
• Coordination for Spravato® administration and monitoring
• Follow-up appointments to assess progress and adjust treatment
• Integration of medicine management and therapy recommendations

Dr. Perry works closely with patients to ensure that every aspect of treatment, from scheduling to aftercare, supports emotional healing and sustainable mental wellness.

What to Expect During Spravato® Treatment

When beginning Spravato® therapy at Daniel Perry MD, you can expect a safe, guided experience every step of the way.

1. Evaluation: Dr. Perry confirms that Spravato® is appropriate for your diagnosis and medical history.
2. Administration: Spravato® is self-administered under direct supervision in our Savannah office.
3. Observation: You will rest comfortably for about two hours as your response is monitored.
4. Follow-Up: Progress is tracked carefully over multiple sessions to measure outcomes and make any needed adjustments.

Our team ensures that every session is private, calm, and supportive, creating an atmosphere where you can focus on recovery and self-care.

Benefits of Spravato® Therapy

Patients who receive Spravato® for treatment-resistant depression in Savannah often report:

• Noticeable improvement in mood within weeks
• Increased energy and motivation
• Reduction in depressive thoughts and emotional numbness
• Better response to concurrent therapies or medications

Every experience is unique, and Dr. Perry ensures that patients receive personalized medical attention to achieve the best possible results.

Is Spravato® Right for You?

If you’ve tried two or more antidepressants without adequate improvement, Spravato® may be a suitable next step.
Dr. Perry evaluates each case individually to determine the safest and most effective treatment plan.

Our practice proudly serves Savannah, Pooler, Richmond Hill, and surrounding Georgia communities, offering trusted psychiatric care that prioritizes safety, accessibility, and compassion.

Contact Daniel Perry MD

If you are struggling with treatment-resistant depression, you don’t have to face it alone.

Contact Daniel Perry MD, today to learn more about Spravato® therapy in Savannah, GA, and take the first step toward feeling better.

Contact Information:

315 Commercial Drive, Suite D-6, Savannah, GA 31406

Phone: (912) 513-2888

‍